Intensive Protocol vs Usual Care Protocol: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.356 | 0.343 | 0.369 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.364 | 0.35 | 0.377 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0077 | -0.0266 | 0.0112 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.979 | 0.929 | 1.03 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.967 | 0.891 | 1.05 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer death from any cause on Intensive Protocol than on Usual Care Protocol | 130 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Intensive Protocol | Facility randomized to follow the intensive nutritional supplement protocol~Nutritional Supplement: Selection of which supplement to give to the patients will be left to the dialysis unit's governing body as this study is not interested in a specific supplement's effect on nutrient restoration and subsequent outcomes but rather on oral replacement of amino acids regardless of the agent used. | 1,827 | 5,133 | EG001 | ClinicalTrials.gov |
| Group 2 | Usual Care Protocol | Facility randomized to follow the usual care nutritional supplement protocol~Nutritional Supplement: Selection of which supplement to give to the patients will be left to the dialysis unit's governing body as this study is not interested in a specific supplement's effect on nutrient restoration and subsequent outcomes but rather on oral replacement of amino acids regardless of the agent used. | 1,732 | 4,763 | EG000 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, all-cause mortality | ClinicalTrials.gov |
| Time frame | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Health Effects of oraL Protein Supplements in HD (The HELPS-HD Trial) | ClinicalTrials.gov |
| NCT number | NCT02933151 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | End Stage Renal Disease | ClinicalTrials.gov |
| Interventions | Nutritional Supplement | ClinicalTrials.gov |
| Lead sponsor | Dialysis Clinic, Inc. | ClinicalTrials.gov |
| Results first posted | 2024-11-05 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02933151?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.