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Comparison · NCT02981407-6a5c4903

Liberal Transfusion Strategy vs Restrictive Transfusion Strategy: Ischemia Driven Unscheduled Coronary Revascularization

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Liberal Transfusion Strategy vs Restrictive Transfusion Strategy: Ischemia Driven Unscheduled Coronary Revascularization. Trial comparisons, record NCT02981407-6a5c4903. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02981407-6a5c4903

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.02220.01630.0302wilson
Risk in group 20.02460.01830.033wilson
Risk difference, group 1 minus group 2-0.00236-0.01260.00782newcombe hybrid score
Risk ratio, group 1 over group 20.9040.5891.39log
Odds ratio, group 1 over group 20.9020.5821.4log
Number needed to treat, for one fewer participant with the outcome on Liberal Transfusion Strategy than on Restrictive Transfusion Strategy423from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Liberal Transfusion Strategy
Red blood cell transfusion - One unit of packed red cells is transfused following randomization followed by enough red blood cell units to raise the hemoglobin concentration above 10 g/dL any time the hemoglobin concentration is detected to be below 10g/dL during the hospitalization for up to 30 days.~Red Blood Cell Transfusion: Transfusion of packed red blood cell units
391,755OG000
Group 2Restrictive Transfusion Strategy
Permitted to receive a red blood cell transfusion if the blood count is below 8 g/dL and the physician believes it is in the patient's best interest. A transfusion will be strongly recommended if the blood count drops to less than 7 g/dL. If the patient has symptoms of angina (e.g., chest discomfort described as pressure or heaviness) that do not go away with medication, a blood transfusion will be ordered regardless of the blood count.~Red Blood Cell Transfusion: Transfusion of packed red blood cell units
431,749OG001

Outcome

Type
OTHER_PRE_SPECIFIED
Title
Ischemia Driven Unscheduled Coronary Revascularization
Description
Time frame
Within 30 days of randomization
Population

Source ClinicalTrials.gov

Trial

Title
Myocardial Ischemia and Transfusion
NCT number
NCT02981407
Phases
PHASE3
Conditions
Myocardial Infarction, Anemia
Interventions
Red Blood Cell Transfusion
Lead sponsor
Rutgers, The State University of New Jersey
Results first posted
2024-05-09

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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