Low Molecular Weight Heparin (LMWH)-Enoxaparin vs Acetylsalicylic Acid (ASA)-Aspirin: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.00736 | 0.00551 | 0.00984 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0077 | 0.0058 | 0.0102 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.000339 | -0.00347 | 0.00278 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.956 | 0.636 | 1.44 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.956 | 0.634 | 1.44 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer death from any cause on Low Molecular Weight Heparin (LMWH)-Enoxaparin than on Acetylsalicylic Acid (ASA)-Aspirin | 2,950 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Low Molecular Weight Heparin (LMWH)-Enoxaparin | Injection of 30 mg enoxaparin, twice a day via injection~Low Molecular Weight Heparin (LMWH): The LMWH intervention will be 30 mg enoxaparin subcutaneous (under the skin) twice a day with variations in dosing allowed, per the standard of care at sites, as needed for patients who are very obese or exhibit renal dysfunction. | 45 | 6,110 | EG000 | ClinicalTrials.gov |
| Group 2 | Acetylsalicylic Acid (ASA)-Aspirin | Enteral ingestion or administration of 81 mg ASA, twice a day~Acetylsalicylic acid: The Aspirin intervention will be 81 mg enteral (by mouth, feeding tube or rectal) twice a day with no variation in dosing allowed. | 47 | 6,101 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, all-cause mortality | ClinicalTrials.gov |
| Time frame | 90 days | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | PREVENTion of Clot in Orthopaedic Trauma | ClinicalTrials.gov |
| NCT number | NCT02984384 | ClinicalTrials.gov |
| Phases | PHASE3 | ClinicalTrials.gov |
| Conditions | Blood Clot, Trauma | ClinicalTrials.gov |
| Interventions | Acetylsalicylic acid, Low Molecular Weight Heparin (LMWH) | ClinicalTrials.gov |
| Lead sponsor | Major Extremity Trauma Research Consortium | ClinicalTrials.gov |
| Results first posted | 2024-05-14 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT02984384?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.