Comparison · NCT02990910-c50cc3f2
Individualized Opioid Analgesia vs Conventional Opioid Analgesia: The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Individualized Opioid Analgesia vs Conventional Opioid Analgesia: The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events. Trial comparisons, record NCT02990910-c50cc3f2. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02990910-c50cc3f2
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.119 | 0.0748 | 0.185 | wilson | |
| Risk in group 2 | 0.223 | 0.16 | 0.302 | wilson | |
| Risk difference, group 1 minus group 2 | -0.104 | -0.194 | -0.0126 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.535 | 0.306 | 0.938 | log | |
| Odds ratio, group 1 over group 2 | 0.472 | 0.243 | 0.919 | log | |
| Number needed to treat, for one fewer participant with the outcome on Individualized Opioid Analgesia than on Conventional Opioid Analgesia | 9.65 | 5.15 | 79.5 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Individualized Opioid Analgesia | One group: positive result 10μg/kg morphine; negative result 50μg/kg morphine.Scored every 10 minutes until CHEOPS\<=6 and Aldrete score\>9.~personalized opioid analgesia: (a)positive result 10μg/kg morphine; negative result 50μg/kg morphine. | 16 | 134 | OG000 |
| Group 2 | Conventional Opioid Analgesia | Another group: all received 25μg/kg morphine .Scored every 10 minutes until CHEOPS\<=6 and Aldrete score\>9.~conventional opioid analgesia: (b) all received 25μg/kg morphine | 29 | 130 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events
- Description
The medical interventions included instrumentation of the airway, bag/mask ventilation, and/or drug administration (succinylcholine, albuterol, or naloxone), which were classified as major medical interventions. The medical interventions also included repositioning of the child's airway, chin lift/jaw thrust maneuvers, and/or escalating to an oxygen mask, which were classified as minor medical interventions. Since oxygen by nasal cannula was delivered to all children recovering from anesthesia, escalating to an oxygen mask implied the patient need but higher concentration of oxygen to maintain SpO2 ≥ 95%.
- Time frame
- Time from entering the PACU until the patient leaves,approx 1 hour.
- Population
Source ClinicalTrials.gov
Trial
- Title
- Individualized Analgesia After Adenotonsillectomy
- NCT number
- NCT02990910
- Phases
- NA
- Conditions
- Analgesia
- Interventions
- Individualized opioid analgesia, conventional opioid analgesia
- Lead sponsor
- Children's Hospital of Fudan University
- Results first posted
- 2017-08-09
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT02990910?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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