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Comparison · NCT02990910-deaths

Individualized Opioid Analgesia vs Conventional Opioid Analgesia: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Individualized Opioid Analgesia vs Conventional Opioid Analgesia: deaths from any cause. Trial comparisons, record NCT02990910-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT02990910-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.1190.07480.185wilson
Risk in group 20.2230.160.302wilson
Risk difference, group 1 minus group 2-0.104-0.194-0.0126newcombe hybrid score
Risk ratio, group 1 over group 20.5350.3060.938log
Odds ratio, group 1 over group 20.4720.2430.919log
Number needed to treat, for one fewer death from any cause on Individualized Opioid Analgesia than on Conventional Opioid Analgesia9.655.1579.5from the risk difference interval

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Individualized Opioid Analgesia
One group: positive result 10μg/kg morphine; negative result 50μg/kg morphine.Scored every 10 minutes until CHEOPS\<=6 and Aldrete score\>9.~personalized opioid analgesia: (a)positive result 10μg/kg morphine; negative result 50μg/kg morphine.
16134EG000
Group 2Conventional Opioid AnalgesiaAnother group: all received 25μg/kg morphine .Scored every 10 minutes until CHEOPS\<=6 and Aldrete score\>9.~conventional opioid analgesia: (b) all received 25μg/kg morphine29130EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Time from entering the PACU until the patient leaves,approx 1 hour.

Source ClinicalTrials.gov

Trial

Title
Individualized Analgesia After Adenotonsillectomy
NCT number
NCT02990910
Phases
NA
Conditions
Analgesia
Interventions
Individualized opioid analgesia, conventional opioid analgesia
Lead sponsor
Children's Hospital of Fudan University
Results first posted
2017-08-09

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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