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Comparison · NCT03002623-deaths

Anaplastic Thyroid Cancer vs Poorly Differentiated/Variants of Thyroid Cancer: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Anaplastic Thyroid Cancer vs Poorly Differentiated/Variants of Thyroid Cancer: deaths from any cause. Trial comparisons, record NCT03002623-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03002623-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.50.150.85wilson
Risk in group 20.3330.06150.792wilson
Risk difference, group 1 minus group 20.167-0.4110.61newcombe hybrid score
Risk ratio, group 1 over group 21.50.239.8log
Odds ratio, group 1 over group 220.090244.4log
Number needed to harm, for one more death from any cause on Anaplastic Thyroid Cancer than on Poorly Differentiated/Variants of Thyroid Cancer6from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Anaplastic Thyroid CancerCUDC-907 for anaplastic thyroid cancer CUDC-907: 60 mg (2 capsules of 30 mg capsules) will be given orally once a day, 5 days on and 2 days off.24EG000
Group 2Poorly Differentiated/Variants of Thyroid CancerCUDC-907 for Poorly differentiated and aggressive variants of differentiated thyroid cancer.~CUDC-907: 60 mg (2 capsules of 30 mg capsules) will be given orally once a day, 5 days on and 2 days off.13EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Date treatment consent signed to date off study, approximately 12 months and 13 days.

Source ClinicalTrials.gov

Trial

Title
CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid Cancer
NCT number
NCT03002623
Phases
PHASE2
Conditions
Thyroid Neoplasms, Poorly Differentiated and Undifferentiated Thyroid Cancer, Differentiated Thyroid Cancer
Interventions
CUDC-907
Lead sponsor
National Cancer Institute (NCI)
Results first posted
2018-12-21

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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