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Comparison · NCT03002623-sae

Anaplastic Thyroid Cancer vs Poorly Differentiated/Variants of Thyroid Cancer: serious adverse events

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Anaplastic Thyroid Cancer vs Poorly Differentiated/Variants of Thyroid Cancer: serious adverse events. Trial comparisons, record NCT03002623-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03002623-sae

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.50.150.85wilson
Risk in group 20.3330.06150.792wilson
Risk difference, group 1 minus group 20.167-0.4110.61newcombe hybrid score
Risk ratio, group 1 over group 21.50.239.8log
Odds ratio, group 1 over group 220.090244.4log
Number needed to harm, for one more participant with a serious adverse event on Anaplastic Thyroid Cancer than on Poorly Differentiated/Variants of Thyroid Cancer6from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Anaplastic Thyroid CancerCUDC-907 for anaplastic thyroid cancer CUDC-907: 60 mg (2 capsules of 30 mg capsules) will be given orally once a day, 5 days on and 2 days off.24EG000
Group 2Poorly Differentiated/Variants of Thyroid CancerCUDC-907 for Poorly differentiated and aggressive variants of differentiated thyroid cancer.~CUDC-907: 60 mg (2 capsules of 30 mg capsules) will be given orally once a day, 5 days on and 2 days off.13EG001

Harm

What it counts
Total, serious adverse events
Time frame
Date treatment consent signed to date off study, approximately 12 months and 13 days.

Source ClinicalTrials.gov

Trial

Title
CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid Cancer
NCT number
NCT03002623
Phases
PHASE2
Conditions
Thyroid Neoplasms, Poorly Differentiated and Undifferentiated Thyroid Cancer, Differentiated Thyroid Cancer
Interventions
CUDC-907
Lead sponsor
National Cancer Institute (NCI)
Results first posted
2018-12-21

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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