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Comparison · NCT03036124-deaths

Dapa 10mg vs Placebo: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Dapa 10mg vs Placebo: deaths from any cause. Trial comparisons, record NCT03036124-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03036124-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.1210.1080.135wilson
Risk in group 20.1410.1270.155wilson
Risk difference, group 1 minus group 2-0.0198-0.0391-0.000639newcombe hybrid score
Risk ratio, group 1 over group 20.8590.7410.995log
Odds ratio, group 1 over group 20.8390.7090.994log
Number needed to treat, for one fewer death from any cause on Dapa 10mg than on Placebo50.425.61,560from the risk difference interval

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Dapa 10mgDapagliflozin 10 mg, given once daily per oral use.2862,368EG000
Group 2PlaceboPlacebo tablet to match dapagliflozin 10 mg, given once daily per oral use.3332,368EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Up to 28.3 months.

Source ClinicalTrials.gov

Trial

Title
Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure
NCT number
NCT03036124
Phases
PHASE3
Conditions
Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions
Dapagliflozin, Placebo
Lead sponsor
AstraZeneca
Results first posted
2020-09-01

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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