Comparison · NCT03040726-deaths
Blinded Intervention gp. vs Placebo gp.: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Blinded Intervention gp. vs Placebo gp.: deaths from any cause. Trial comparisons, record NCT03040726-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03040726-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.1 | 0.0346 | 0.256 | wilson | |
| Risk in group 2 | 0.0465 | 0.0128 | 0.155 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0535 | -0.0728 | 0.213 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.15 | 0.382 | 12.1 | log | |
| Odds ratio, group 1 over group 2 | 2.28 | 0.357 | 14.5 | log | |
| Number needed to harm, for one more death from any cause on Blinded Intervention gp. than on Placebo gp. | 18.7 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Blinded Intervention gp. | Took one Netupitant/Palonosetron (NEPA) capsule every 5 days for 2 doses | 3 | 30 | EG000 |
| Group 2 | Placebo gp. | Took one Placebo capsule every 5 days for 2 doses | 2 | 43 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Study Day 15
Source ClinicalTrials.gov
Trial
- Title
- Netupitant and Palonosetron Hydrochloride in Preventing Chronic Nausea and Vomiting in Patients With Cancer
- NCT number
- NCT03040726
- Phases
- PHASE2, PHASE3
- Conditions
- Malignant Neoplasm, Nausea, Vomiting
- Interventions
- Netupitant, Palonosetron, Palonosetron Hydrochloride, Placebo, Questionnaire Administration
- Lead sponsor
- M.D. Anderson Cancer Center
- Results first posted
- 2023-10-17
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03040726?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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