Comparison · NCT03058666-e31597bd
Aerosolized Calfactant vs Usual Care: Respiratory Support Requirements
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Aerosolized Calfactant vs Usual Care: Respiratory Support Requirements. Trial comparisons, record NCT03058666-e31597bd. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03058666-e31597bd
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.27 | 0.218 | 0.329 | wilson | |
| Risk in group 2 | 0.525 | 0.462 | 0.588 | wilson | |
| Risk difference, group 1 minus group 2 | -0.256 | -0.337 | -0.169 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.513 | 0.404 | 0.653 | log | |
| Odds ratio, group 1 over group 2 | 0.334 | 0.228 | 0.489 | log | |
| Number needed to treat, for one fewer participant with the outcome on Aerosolized Calfactant than on Usual Care | 3.91 | 2.96 | 5.93 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Aerosolized Calfactant | Aerosolized Calfactant: Aerosolization of Infasurf at 6ml/kg via the modified Solarys aerosol generator.~Solarys: Aerosolization of Infasurf at 6ml/kg via the modified Solarys aerosol generator. | 65 | 241 | OG000 |
| Group 2 | Usual Care | There will be no protocol driven interventions in the usual care group. | 124 | 236 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Respiratory Support Requirements
- Description
- Difference of Respiratory support at 28 days
- Time frame
- 28 days
- Population
Source ClinicalTrials.gov
Trial
- Title
- Comparison of Aerosol Delivery of Infasurf to Usual Care in Spontaneously Breathing RDS Patients
- NCT number
- NCT03058666
- Phases
- PHASE3
- Conditions
- Respiratory Distress Syndrome
- Interventions
- Aerosolized Calfactant, Solarys
- Lead sponsor
- ONY
- Results first posted
- 2024-05-29
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03058666?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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