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Comparison · NCT03073486-deaths

Olumacostat Glasaretil Gel, 5.0% vs Olumacostat Glasaretil Gel, Vehicle: deaths from any cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Olumacostat Glasaretil Gel, 5.0% vs Olumacostat Glasaretil Gel, Vehicle: deaths from any cause. Trial comparisons, record NCT03073486-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03073486-deaths

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 1000.00776wilson
Risk in group 2000.0153wilson
Risk difference, group 1 minus group 20-0.01530.00776newcombe hybrid score
Risk ratio, group 1 over group 2loga group has no participants with the outcome
Odds ratio, group 1 over group 2loga cell of the two-by-two table is zero
Number needed to harmfrom the risk difference intervalthe two groups' risks are equal

Groups2

Group 2 names the comparator: vehicle.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Olumacostat Glasaretil Gel, 5.0%Olumacostat Glasaretil Gel, 5.0%, applied twice daily to the face for 12 weeks0491EG000
Group 2Olumacostat Glasaretil Gel, VehicleOlumacostat Glasaretil Gel, Vehicle, applied twice daily to the face for 12 weeks0248EG001

Harm

What it counts
Total, all-cause mortality
Time frame
Baseline to Week 12

Source ClinicalTrials.gov

Trial

Title
A Study of Olumacostat Glasaretil Gel in Subjects With Acne Vulgaris
NCT number
NCT03073486
Phases
PHASE3
Conditions
Acne Vulgaris
Interventions
Olumacostat Glasaretil Gel, 5.0%, Olumacostat Glasaretil Gel, Vehicle
Lead sponsor
Dermira, Inc.
Results first posted
2019-02-05

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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