Comparison · NCT03170362-768c88f5
Intervention Group vs Delay Results Group: Depression Response
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Intervention Group vs Delay Results Group: Depression Response. Trial comparisons, record NCT03170362-768c88f5. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03170362-768c88f5
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.321 | 0.289 | 0.355 | wilson | |
| Risk in group 2 | 0.274 | 0.244 | 0.307 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0465 | 0.000845 | 0.092 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.17 | 1 | 1.36 | log | |
| Odds ratio, group 1 over group 2 | 1.25 | 1 | 1.56 | log | |
| Number needed to treat, for one more participant with the outcome on Intervention Group than on Delay Results Group | 21.5 | 10.9 | 1,180 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Intervention Group | Pharmacogenetic test results will be provided to the provider within 72 hours of randomization in order to facilitate choice in selecting antidepressants.~Pharmacogenetic Test: The intervention is a battery of pharmacogenetic test results that mostly affect the metabolism of antidepressants and other medications. | 242 | 754 | OG000 |
| Group 2 | Delay Results Group | The comparator arm will not receive results at the time of randomization but will get results after the 24 week assessment (thus the results are delayed). | 216 | 787 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Depression Response
- Description
The investigators will use the Patient Health Questionnaire 9 (PHQ9) as a self assessed marker of depression remission. The scale ranges from 0 to 27 with lower scores indicating less depression severity. Response was measured by a 50% reduction in scores from baseline to each time point.
- Time frame
- 24 weeks
- Population
Source ClinicalTrials.gov
Trial
- Title
- PRIME Care (PRecision Medicine In MEntal Health Care)
- NCT number
- NCT03170362
- Phases
- NA
- Conditions
- Major Depression
- Interventions
- Pharmacogenetic Test
- Lead sponsor
- VA Office of Research and Development
- Results first posted
- 2024-05-28
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03170362?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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