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Comparison · NCT03229941-18f86e53

Restrictive vs Liberal: All-cause Mortality at 1 Year After Randomization

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Restrictive vs Liberal: All-cause Mortality at 1 Year After Randomization. Trial comparisons, record NCT03229941-18f86e53. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03229941-18f86e53

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.150.1250.178wilson
Risk in group 20.1410.1160.169wilson
Risk difference, group 1 minus group 20.00907-0.02850.0464newcombe hybrid score
Risk ratio, group 1 over group 21.060.8231.38log
Odds ratio, group 1 over group 21.080.7961.45log
Number needed to treat, for one more participant with the outcome on Restrictive than on Liberal110from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1RestrictiveBlood transfusion trigger: Hb\<7gm/dl105701OG000
Group 2LiberalBlood transfusion trigger: Hb\<10gm/dl94668OG001

Outcome

Type
SECONDARY
Title
All-cause Mortality at 1 Year After Randomization
Description
The investigators will determine vital status by telephoning participants after hospital discharge, by searching the electronic medical record and the Death Ascertainment File.
Time frame
12 months after randomization
Population
Intent to treat population

Source ClinicalTrials.gov

Trial

Title
Transfusion Trigger After Operations in High Cardiac Risk Patients
NCT number
NCT03229941
Phases
NA
Conditions
Myocardial Infarction, Coronary Revascularization, Acute Renal Failure
Interventions
Blood Transfusion
Lead sponsor
VA Office of Research and Development
Results first posted
2025-09-05

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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