Comparison · NCT03229941-3d02001c
Restrictive vs Liberal: A Composite Endpoint of All-cause Mortality, MI, Coronary Revascularization, Acute Renal Failure, or Postoperative Ischemic Stroke
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Restrictive vs Liberal: A Composite Endpoint of All-cause Mortality, MI, Coronary Revascularization, Acute Renal Failure, or Postoperative Ischemic Stroke. Trial comparisons, record NCT03229941-3d02001c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03229941-3d02001c
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.064 | 0.0482 | 0.0846 | wilson | |
| Risk in group 2 | 0.0485 | 0.0348 | 0.0674 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0155 | -0.00913 | 0.0402 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.32 | 0.852 | 2.04 | log | |
| Odds ratio, group 1 over group 2 | 1.34 | 0.845 | 2.13 | log | |
| Number needed to treat, for one more participant with the outcome on Restrictive than on Liberal | 64.6 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Restrictive | Blood transfusion trigger: Hb\<7gm/dl | 45 | 703 | OG000 |
| Group 2 | Liberal | Blood transfusion trigger: Hb\<10gm/dl | 33 | 680 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- A Composite Endpoint of All-cause Mortality, MI, Coronary Revascularization, Acute Renal Failure, or Postoperative Ischemic Stroke
- Description
- A composite endpoint of all-cause mortality, MI, coronary revascularization, acute renal failure, or postoperative ischemic stroke.
- Time frame
- 30 days after randomization
- Population
- Intent to treat population
Source ClinicalTrials.gov
Trial
- Title
- Transfusion Trigger After Operations in High Cardiac Risk Patients
- NCT number
- NCT03229941
- Phases
- NA
- Conditions
- Myocardial Infarction, Coronary Revascularization, Acute Renal Failure
- Interventions
- Blood Transfusion
- Lead sponsor
- VA Office of Research and Development
- Results first posted
- 2025-09-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03229941?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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