Comparison · NCT03282799-16b8b19a
Standard Dose Etonogestrel Implant vs Increased Dose Etonogestrel Implant: Proportion of Participants That Ovulate During Month 12
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Standard Dose Etonogestrel Implant vs Increased Dose Etonogestrel Implant: Proportion of Participants That Ovulate During Month 12. Trial comparisons, record NCT03282799-16b8b19a. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03282799-16b8b19a
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.559 | 0.395 | 0.711 | wilson | |
| Risk in group 2 | 0.0556 | 0.0154 | 0.181 | wilson | |
| Risk difference, group 1 minus group 2 | 0.503 | 0.296 | 0.661 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 10.1 | 2.53 | 40 | log | |
| Odds ratio, group 1 over group 2 | 21.5 | 4.44 | 104 | log | |
| Number needed to treat, for one more participant with the outcome on Standard Dose Etonogestrel Implant than on Increased Dose Etonogestrel Implant | 1.99 | 1.51 | 3.38 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Standard Dose Etonogestrel Implant | Single 68 mg etonogestrel implant~etonogestrel implant: The etonogestrel implant is an contraceptive implant that is placed into the upper arm. | 19 | 34 | OG000 |
| Group 2 | Increased Dose Etonogestrel Implant | Two 68 mg (136 mg total) etonogestrel implants~etonogestrel implant: The etonogestrel implant is an contraceptive implant that is placed into the upper arm. | 2 | 36 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Proportion of Participants That Ovulate During Month 12
- Description
Proportion of participants that experience at least one ovulation during month 12 of etonogestrel implant use. Serum progesterone concentrations are measured weekly during month 12 (weeks 45-48). Ovulation is defined as endogenous progesterone concentrations of \>3 ng/mL.
- Time frame
- 12 months
- Population
- One participant in the standard dose arm was withdrawn at week 1 of the study due to pregnancy, and one was withdrawn at week 45 due to a mental health condition.
Source ClinicalTrials.gov
Trial
- Title
- Pharmacologic Strategies for the Etonogestrel Implant in HIV-Infected Women
- NCT number
- NCT03282799
- Phases
- PHASE2
- Conditions
- HIV/AIDS, Contraception
- Interventions
- etonogestrel implant
- Lead sponsor
- Catherine Anne Chappell
- Results first posted
- 2024-09-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03282799?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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