Comparison · NCT03282799-a32c734b
Standard Dose Etonogestrel Implant vs Increased Dose Etonogestrel Implant: Proportion of Participants That Ovulate During Month 3
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Standard Dose Etonogestrel Implant vs Increased Dose Etonogestrel Implant: Proportion of Participants That Ovulate During Month 3. Trial comparisons, record NCT03282799-a32c734b. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03282799-a32c734b
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.314 | 0.186 | 0.48 | wilson | |
| Risk in group 2 | 0 | 0 | 0.0964 | wilson | |
| Risk difference, group 1 minus group 2 | 0.314 | 0.153 | 0.48 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one more participant with the outcome on Standard Dose Etonogestrel Implant than on Increased Dose Etonogestrel Implant | 3.18 | 2.08 | 6.52 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Standard Dose Etonogestrel Implant | Single 68 mg etonogestrel implant~etonogestrel implant: The etonogestrel implant is an contraceptive implant that is placed into the upper arm. | 11 | 35 | OG000 |
| Group 2 | Increased Dose Etonogestrel Implant | Two 68 mg (136 mg total) etonogestrel implants~etonogestrel implant: The etonogestrel implant is an contraceptive implant that is placed into the upper arm. | 0 | 36 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Proportion of Participants That Ovulate During Month 3
- Description
Proportion of participants that experience at least one ovulation during month 3 of etonogestrel implant use. Serum progesterone concentrations are measured weekly during month 3 (weeks 9-12). Ovulation is defined as endogenous progesterone concentrations of \>3 ng/mL.
- Time frame
- 3 months
- Population
- One participant in the standard dose arm was withdrawn at week 1 of the study due to pregnancy.
Source ClinicalTrials.gov
Trial
- Title
- Pharmacologic Strategies for the Etonogestrel Implant in HIV-Infected Women
- NCT number
- NCT03282799
- Phases
- PHASE2
- Conditions
- HIV/AIDS, Contraception
- Interventions
- etonogestrel implant
- Lead sponsor
- Catherine Anne Chappell
- Results first posted
- 2024-09-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03282799?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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