Comparison · NCT03284398-cab16a02
Three-Chambered Bag (3CB) vs Hospital-compounded Bag (HCB): Use of Vasopressor Treatment
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Three-Chambered Bag (3CB) vs Hospital-compounded Bag (HCB): Use of Vasopressor Treatment. Trial comparisons, record NCT03284398-cab16a02. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03284398-cab16a02
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.149 | 0.136 | 0.163 | wilson | |
| Risk in group 2 | 0.3 | 0.272 | 0.33 | wilson | |
| Risk difference, group 1 minus group 2 | -0.151 | -0.183 | -0.12 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.496 | 0.435 | 0.566 | log | |
| Odds ratio, group 1 over group 2 | 0.408 | 0.344 | 0.485 | log | |
| Number needed to treat, for one fewer participant with the outcome on Three-Chambered Bag (3CB) than on Hospital-compounded Bag (HCB) | 6.62 | 5.46 | 8.34 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Three-Chambered Bag (3CB) | Hospitalized adults (≥18 years) who received PN containing all three major macronutrients via industrially-compounded 3CB for ≥3 consecutive days during the observation period (January 1, 2013 to December 31, 2015). | 410 | 2,753 | OG000 |
| Group 2 | Hospital-compounded Bag (HCB) | Hospitalized adults (≥18 years) who received PN containing all three major macronutrients via hospital-compounded all-in-one bag for ≥3 consecutive days during the observation period (January 1, 2013 to December 31, 2015). | 291 | 970 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Use of Vasopressor Treatment
- Description
- Percentages of patients requiring vasopressor support during PN treatment
- Time frame
- Patients requiring vasopressor support at any time during treatment with PN
- Population
Source ClinicalTrials.gov
Trial
- Title
- Three-Chamber Bags Retrospective Study in Spain
- NCT number
- NCT03284398
- Phases
- Conditions
- Parenteral Nutrition, Blood Stream Infection
- Interventions
- Lead sponsor
- Fresenius Kabi
- Results first posted
- 2021-01-08
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03284398?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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