Transcranial Magnetic Stimulation vs Sham Transcranial Magnetic Stimulation: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.0263 | 0.00466 | 0.135 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0488 | 0.0135 | 0.161 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0225 | -0.137 | 0.0918 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.539 | 0.051 | 5.71 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.527 | 0.0458 | 6.06 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with a serious adverse event on Transcranial Magnetic Stimulation than on Sham Transcranial Magnetic Stimulation | 44.5 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: sham.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Transcranial Magnetic Stimulation | Active-repetitive transcranial magnetic stimulation (rTMS) at the left motor cortex.~Transcranial Magnetic Stimulation: Active-repetitive transcranial magnetic stimulation (rTMS) at the left motor cortex.~Magnetic resonance imaging (MRI): Brain imaging will be done via MRI prior to the first rTMS/Sham TMS session. Imaging will allow investigators to target specific areas in the brain. | 1 | 38 | EG000 | ClinicalTrials.gov |
| Group 2 | Sham Transcranial Magnetic Stimulation | Sham rTMS will consist of the same parameters as active, however, the subject will not receive the actual magnetic stimulation to the left motor cortex.~Sham Transcranial Magnetic Stimulation: Sham rTMS will consist of the same parameters as active, however, the subject will not receive the actual magnetic stimulation to the left motor cortex due to the use of a double sided Active/Sham coil used specifically for research studies.~Magnetic resonance imaging (MRI): Brain imaging will be done via MRI prior to the first rTMS/Sham TMS session. Imaging will allow investigators to target specific areas in the brain. | 2 | 41 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, serious adverse events | ClinicalTrials.gov |
| Time frame | Up to 5 years | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation | ClinicalTrials.gov |
| NCT number | NCT03314584 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Traumatic Brain Injury (TBI) | ClinicalTrials.gov |
| Interventions | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation, Magnetic resonance imaging (MRI) | ClinicalTrials.gov |
| Lead sponsor | VA Office of Research and Development | ClinicalTrials.gov |
| Results first posted | 2025-08-07 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT03314584?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.