Comparison · NCT03318783-6f31b4ba
GSK2256294 vs Placebo: Number of Participants With New Stroke on Hospital Discharge Imaging
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. GSK2256294 vs Placebo: Number of Participants With New Stroke on Hospital Discharge Imaging. Trial comparisons, record NCT03318783-6f31b4ba. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03318783-6f31b4ba
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.1 | 0.0179 | 0.404 | wilson | |
| Risk in group 2 | 0.111 | 0.0199 | 0.435 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0111 | -0.345 | 0.306 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.9 | 0.0654 | 12.4 | log | |
| Odds ratio, group 1 over group 2 | 0.889 | 0.0474 | 16.7 | log | |
| Number needed to treat, for one fewer participant with the outcome on GSK2256294 than on Placebo | 90 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | GSK2256294 | 10mg capsules of GSK2256294 will be administered in a single dose once daily enterally for a duration of 10 days.~GSK2256294: GSK2256294 will be administered in a single dose once daily enteral for a duration of 10 days. | 1 | 10 | OG000 |
| Group 2 | Placebo | 10mg matched placebo capsules will be administered in a single dose once daily enterally for a duration of 10 days.~Placebo: Placebo will be administered in a single dose once daily enteral for a duration of 10 days. | 1 | 9 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- OTHER_PRE_SPECIFIED
- Title
- Number of Participants With New Stroke on Hospital Discharge Imaging
- Description
The last head CT or other brain imaging to detect the presence of a new area of cerebral infarction will be reviewed at the time of hospital discharge. A cerebral infarction will be defined as a one identified on hospital discharge that was not present on imaging between 24-48 hours after aneurysm occlusion, and not attributable to other causes such as surgical clipping or endovascular treatment. Hypodensities resulting from extraventricular drains or residual intraparencyhmal hematomas will not be considered new strokes.
- Time frame
- 90 days
- Population
Source ClinicalTrials.gov
Trial
- Title
- Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial
- NCT number
- NCT03318783
- Phases
- PHASE1, PHASE2
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Vasospasm, Cerebral, Endothelial Dysfunction
- Interventions
- GSK2256294, Placebo
- Lead sponsor
- Oregon Health and Science University
- Results first posted
- 2021-01-22
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03318783?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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