Cohort 2011 vs Cohort 2019: Number of Participants With Depression

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measures 6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

Measure	Value	95% interval, lower	95% interval, upper	Method	Source
Risk in group 1	0.111	0.102	0.121	wilson	ClinicalTrials.gov
Risk in group 2	0.0697	0.061	0.0796	wilson	ClinicalTrials.gov
Risk difference, group 1 minus group 2	0.0415	0.0284	0.0544	newcombe hybrid score	ClinicalTrials.gov
Risk ratio, group 1 over group 2	1.6	1.37	1.86	log	ClinicalTrials.gov
Odds ratio, group 1 over group 2	1.67	1.41	1.98	log	ClinicalTrials.gov
Number needed to treat, for one more participant with the outcome on Cohort 2011 than on Cohort 2019	24.1	18.4	35.3	from the risk difference interval	ClinicalTrials.gov

Groups 2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

Group	Title	Description	With the outcome	Analysed	ClinicalTrials.gov code	Source
Group 1	Cohort 2011	A total of 4753 persons participated at baseline between 2011 and 2012.	510	4,583	OG000	ClinicalTrials.gov
Group 2	Cohort 2019	3,002 persons participated at this baseline between 2019 and 2021	203	2,911	OG001	ClinicalTrials.gov

Outcome 5

Field	Value	Source
Type	SECONDARY	ClinicalTrials.gov
Title	Number of Participants With Depression	ClinicalTrials.gov
Description	Measure: The World Health Organization Composite International Diagnostic Interview (CIDI). Depression module (WHO-CIDI, 1990).~Construct: Presence of Depression. Final result: Two measures of depression according to Research Diagnostic Criteria.~* Presence of 12 month depression. Values (yes/no).~* Presence of lifetime depression. Values (yes/no).	ClinicalTrials.gov
Time frame	Baseline	ClinicalTrials.gov
Population	Proxy respondent were not analysed	ClinicalTrials.gov

Trial 8

Field	Value	Source
Title	Ageing and Health. Spanish Longitudinal Study	ClinicalTrials.gov
NCT number	NCT03343886	ClinicalTrials.gov
Phases		ClinicalTrials.gov
Conditions	Health, Subjective, Disability, Evaluation, Chronic Disease, Mental Disorder, Aging, Loneliness, Cognitive Decline, Well-being	ClinicalTrials.gov
Interventions		ClinicalTrials.gov
Lead sponsor	Fundación de Investigación Biomédica - Hospital Universitario de La Princesa	ClinicalTrials.gov
Results first posted	2024-10-15	ClinicalTrials.gov
Results on ClinicalTrials.gov	https://clinicaltrials.gov/study/NCT03343886?tab=results	ClinicalTrials.gov

Source 4

Field	Value	Source
Release	trial-comparisons-2026-03-23-0.1.0	ClinicalTrials.gov
Release manifest SHA-256	f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57	ClinicalTrials.gov
AACT copy	2026-03-23	ClinicalTrials.gov
Tables read	outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet	ClinicalTrials.gov

The same record as JSON

Release trial-comparisons-2026-03-23-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.