Comparison · NCT03348683-516ab3e3
Propranolol vs Placebo: Number of Neonates With Neonatal Outcome Composite Score = 1
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Propranolol vs Placebo: Number of Neonates With Neonatal Outcome Composite Score = 1. Trial comparisons, record NCT03348683-516ab3e3. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03348683-516ab3e3
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.174 | 0.116 | 0.251 | wilson | |
| Risk in group 2 | 0.235 | 0.168 | 0.319 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0617 | -0.163 | 0.0406 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.738 | 0.445 | 1.22 | log | |
| Odds ratio, group 1 over group 2 | 0.683 | 0.362 | 1.29 | log | |
| Number needed to treat, for one fewer participant with the outcome on Propranolol than on Placebo | 16.2 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Propranolol | After induction was started with Foley or misoprostol placement, 30 minutes passed before administration of propranolol 2mg of IV push | 21 | 121 | OG000 |
| Group 2 | Placebo | After induction was started with Foley or misoprostol placement, 30 minutes passed before administration of an equivalent quantity in milliliters of IV normal saline | 28 | 119 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Neonates With Neonatal Outcome Composite Score = 1
- Description
Composite neonatal outcome score was for any of the following morbidity: Neonatal Intensive Care Unit (NICU) admission, respiratory support (CPAP, nasal cannula, intubation), culture proven sepsis, radiographically proven intracranial hemorrhage, necrotizing enterocolitis, hypoglycemia (for those infants who had sugar checked), and neonatal death.~The composite score was computed as a score of 1 for any indication of neonatal morbidity - neonates who experienced at least one morbidity and the components are given equal weights. Patients who had no evidence of the predefined neonatal morbidities are subsequently given a score of 0. The minimum is 0 and maximum is 1.
- Time frame
- Day 1
- Population
Source ClinicalTrials.gov
Trial
- Title
- Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients
- NCT number
- NCT03348683
- Phases
- PHASE2
- Conditions
- Induction of Labor Affected Fetus / Newborn
- Interventions
- Propranolol, Placebo
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Results first posted
- 2019-12-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03348683?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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