Comparison · NCT03348683-bcf629d0
Propranolol vs Placebo: Number of Participants With Maternal Morbidity Composite Score = 1
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Propranolol vs Placebo: Number of Participants With Maternal Morbidity Composite Score = 1. Trial comparisons, record NCT03348683-bcf629d0. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03348683-bcf629d0
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.289 | 0.216 | 0.376 | wilson | |
| Risk in group 2 | 0.412 | 0.327 | 0.502 | wilson | |
| Risk difference, group 1 minus group 2 | -0.123 | -0.238 | -0.00187 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.702 | 0.494 | 0.999 | log | |
| Odds ratio, group 1 over group 2 | 0.581 | 0.34 | 0.994 | log | |
| Number needed to treat, for one fewer participant with the outcome on Propranolol than on Placebo | 8.16 | 4.19 | 536 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Propranolol | After induction was started with Foley or misoprostol placement, 30 minutes passed before administration of propranolol 2mg of IV push | 35 | 121 | OG000 |
| Group 2 | Placebo | After induction was started with Foley or misoprostol placement, 30 minutes passed before administration of an equivalent quantity in milliliters of IV normal saline | 49 | 119 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants With Maternal Morbidity Composite Score = 1
- Description
Composite maternal morbidity score consists of a count of postpartum hemorrhage, transfusion, hysterectomy, placental abruption, chorioamnionitis, shoulder dystocia, episiotomy, higher order laceration, and ICU admission.~The composite score was computed as a score of 1 for any indication of maternal morbidity, that is the participant experienced at least one maternal morbidity, and the components are given equal weights. Participants who had no evidence of the predefined maternal morbidities are subsequently given a score of 0. The minimum is 0 and maximum is 1.
- Time frame
- average of 24 hours
- Population
Source ClinicalTrials.gov
Trial
- Title
- Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients
- NCT number
- NCT03348683
- Phases
- PHASE2
- Conditions
- Induction of Labor Affected Fetus / Newborn
- Interventions
- Propranolol, Placebo
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Results first posted
- 2019-12-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03348683?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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