Comparison · NCT03377790-cc6abdfd
VP-102 vs Placebo: Percentage of Subjects Exhibiting Complete Clearance of All Treatable Molluscum Lesions (Baseline and New) on the Day 84 Visit (EOS)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. VP-102 vs Placebo: Percentage of Subjects Exhibiting Complete Clearance of All Treatable Molluscum Lesions (Baseline and New) on the Day 84 Visit (EOS). Trial comparisons, record NCT03377790-cc6abdfd. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03377790-cc6abdfd
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.463 | 0.387 | 0.54 | wilson | |
| Risk in group 2 | 0.179 | 0.118 | 0.263 | wilson | |
| Risk difference, group 1 minus group 2 | 0.283 | 0.17 | 0.382 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.58 | 1.66 | 4.01 | log | |
| Odds ratio, group 1 over group 2 | 3.94 | 2.19 | 7.08 | log | |
| Number needed to treat, for one more participant with the outcome on VP-102 than on Placebo | 3.53 | 2.62 | 5.87 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | VP-102 | VP-102 Film Forming Solution applied via a prefilled applicator to affected area every 21 days~VP-102: VP-102, a single-use drug device combination product containing (cantharidin) topical solution, 0.7% (w/v). VP-102 Active will be administered to Molluscum lesions | 74 | 160 | OG000 |
| Group 2 | Placebo | Vehicle Film Forming Solution applied via a prefilled applicator to affected area every 21 days~Placebo: Placebo a single-use drug device combination product containing only the vehicle will be administered to Molluscum lesions | 19 | 106 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Percentage of Subjects Exhibiting Complete Clearance of All Treatable Molluscum Lesions (Baseline and New) on the Day 84 Visit (EOS)
- Description
- Percentage of subjects exhibiting complete clearance of all treatable molluscum lesions (baseline and new) on the Day 84 visit (EOS).
- Time frame
- Day 1 (Baseline and new) compared to Day 84 (EOS)
- Population
- ITT Population
Source ClinicalTrials.gov
Trial
- Title
- Cantharidin Application in Molluscum Patients-1
- NCT number
- NCT03377790
- Phases
- PHASE3
- Conditions
- Molluscum Contagiosum
- Interventions
- VP-102 - Cantharidin, Topical Film Forming Solution, Placebo -Topical Film Forming Solution without VP-102
- Lead sponsor
- Verrica Pharmaceuticals Inc.
- Results first posted
- 2021-12-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03377790?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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