Comparison · NCT03377790-d1f74b80
VP-102 vs Placebo: Percentage of Subjects Exhibiting Complete Clearance of All Treatable Molluscum Lesions (Baseline and New) on the Day 42 Visit
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. VP-102 vs Placebo: Percentage of Subjects Exhibiting Complete Clearance of All Treatable Molluscum Lesions (Baseline and New) on the Day 42 Visit. Trial comparisons, record NCT03377790-d1f74b80. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03377790-d1f74b80
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.206 | 0.151 | 0.275 | wilson | |
| Risk in group 2 | 0.0943 | 0.0521 | 0.165 | wilson | |
| Risk difference, group 1 minus group 2 | 0.112 | 0.0221 | 0.193 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.19 | 1.13 | 4.25 | log | |
| Odds ratio, group 1 over group 2 | 2.49 | 1.17 | 5.31 | log | |
| Number needed to treat, for one more participant with the outcome on VP-102 than on Placebo | 8.94 | 5.18 | 45.3 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | VP-102 | VP-102 Film Forming Solution applied via a prefilled applicator to affected area every 21 days~VP-102: VP-102, a single-use drug device combination product containing (cantharidin) topical solution, 0.7% (w/v). VP-102 Active will be administered to Molluscum lesions | 33 | 160 | OG000 |
| Group 2 | Placebo | Vehicle Film Forming Solution applied via a prefilled applicator to affected area every 21 days~Placebo: Placebo a single-use drug device combination product containing only the vehicle will be administered to Molluscum lesions | 10 | 106 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Percentage of Subjects Exhibiting Complete Clearance of All Treatable Molluscum Lesions (Baseline and New) on the Day 42 Visit
- Description
- Percentage of subjects exhibiting complete clearance of all treatable molluscum lesions (baseline and new) on the Day 42 visit.
- Time frame
- Day 1 (Baseline and new) compared to Day 42
- Population
- ITT Population
Source ClinicalTrials.gov
Trial
- Title
- Cantharidin Application in Molluscum Patients-1
- NCT number
- NCT03377790
- Phases
- PHASE3
- Conditions
- Molluscum Contagiosum
- Interventions
- VP-102 - Cantharidin, Topical Film Forming Solution, Placebo -Topical Film Forming Solution without VP-102
- Lead sponsor
- Verrica Pharmaceuticals Inc.
- Results first posted
- 2021-12-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03377790?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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