Comparison · NCT03377803-c0c7d181
VP-102 vs Placebo: Percentage of Subjects Exhibiting a 90% or Greater Reduction of All Treatable Molluscum Lesions (Baseline and New) at the EOS Visit
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. VP-102 vs Placebo: Percentage of Subjects Exhibiting a 90% or Greater Reduction of All Treatable Molluscum Lesions (Baseline and New) at the EOS Visit. Trial comparisons, record NCT03377803-c0c7d181. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03377803-c0c7d181
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.7 | 0.622 | 0.768 | wilson | |
| Risk in group 2 | 0.277 | 0.202 | 0.366 | wilson | |
| Risk difference, group 1 minus group 2 | 0.423 | 0.305 | 0.524 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.53 | 1.84 | 3.47 | log | |
| Odds ratio, group 1 over group 2 | 6.1 | 3.55 | 10.5 | log | |
| Number needed to treat, for one more participant with the outcome on VP-102 than on Placebo | 2.36 | 1.91 | 3.28 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | VP-102 | VP-102 Film Forming Solution applied via a prefilled applicator to affected area every 21 days~VP-102: VP-102 Active will be administered via the applicator to Molluscum lesions~Applicator: Used to apply the topical film forming Active or Placebo to Molluscum. | 105 | 150 | OG000 |
| Group 2 | Placebo | Vehicle Film Forming Solution applied via a prefilled applicator to affected area every 21 days~Placebo: Placebo to be applied via the applicator to Molluscum lesions~Applicator: Used to apply the topical film forming Active or Placebo to Molluscum. | 31 | 112 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- OTHER_PRE_SPECIFIED
- Title
- Percentage of Subjects Exhibiting a 90% or Greater Reduction of All Treatable Molluscum Lesions (Baseline and New) at the EOS Visit
- Description
- Percentage of subjects exhibiting a 90% or greater reduction of all treatable molluscum lesions (baseline and new) at the EOS visit.
- Time frame
- Day 1 (Baseline) compared to Day 84 (EOS)
- Population
- ITT Population
Source ClinicalTrials.gov
Trial
- Title
- Cantharidin Application in Molluscum Patients
- NCT number
- NCT03377803
- Phases
- PHASE3
- Conditions
- Molluscum Contagiosum
- Interventions
- VP-102 - Cantharidin, Topical Film Forming Solution, Placebo -Topical Film Forming Solution without VP-102
- Lead sponsor
- Verrica Pharmaceuticals Inc.
- Results first posted
- 2021-12-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03377803?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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