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Comparison · NCT03409367-8f60a94e

Daily Emollient vs Natural Skin: Provider-diagnosed Atopic Dermatitis at 18 Months

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Daily Emollient vs Natural Skin: Provider-diagnosed Atopic Dermatitis at 18 Months. Trial comparisons, record NCT03409367-8f60a94e. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03409367-8f60a94e

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.2750.2390.313wilson
Risk in group 20.3440.3060.384wilson
Risk difference, group 1 minus group 2-0.0693-0.123-0.0155newcombe hybrid score
Risk ratio, group 1 over group 20.7980.670.952log
Odds ratio, group 1 over group 20.7220.560.93log
Number needed to treat, for one fewer participant with the outcome on Daily Emollient than on Natural Skin14.48.1564.7from the risk difference interval

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Daily Emollient
Parents assigned to the intervention arm receive a lipid-rich emollient and educational materials promoting once daily full-body emollient use until infant age 24 months. Participant choice of over-the-counter emollients: Vaseline, Vanicream, CeraVe Healing Ointment, CeraVe cream, Cetaphil cream: Lipid-rich emollient serving as skin barrier
154561OG000
Group 2Natural Skin
Parents assigned to the control arm receive educational materials promoting general infant skin care guidelines only and asked to refrain from emollient use unless dry skin develops (current standard of care guidelines).
196570OG001

Outcome

Type
SECONDARY
Title
Provider-diagnosed Atopic Dermatitis at 18 Months
Description
Diagnosis of atopic dermatitis (eczema) recorded by primary care providers in health records up to 18 months of age.
Time frame
up to 18 months
Population
Infants with diagnosis of atopic dermatitis at \<=18 months or with no diagnosis and at least one primary care visit in the health record after 15 months of age. Numbers represent participants according to arm randomized, regardless of adherence to study instructions.

Source ClinicalTrials.gov

Trial

Title
A Community-based Assessment of Skin Care, Allergies, and Eczema
NCT number
NCT03409367
Phases
NA
Conditions
Atopic Dermatitis, Atopic Disorders, Eczema, Atopic Eczema
Interventions
Participant choice of over-the-counter emollients: Vaseline, Vanicream, CeraVe Healing Ointment, CeraVe cream, Cetaphil cream
Lead sponsor
Oregon Health and Science University
Results first posted
2025-08-15

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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