2018 School Leavers vs 2019 School Leavers: Estimate the Difference in Carriage Prevalence of Disease Associated Genogroups of N. Meningitidis (A, B, C, W, X, Y) Between School Leavers in 2018 (Year 12 in 2017) and 2019 (Year 12 in 2018), Following a 4CMenB School Immunisation Program
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.0548 | 0.0483 | 0.0622 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0498 | 0.0422 | 0.0587 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.00501 | -0.00603 | 0.0156 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.1 | 0.894 | 1.36 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.11 | 0.888 | 1.38 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on 2018 School Leavers than on 2019 School Leavers | 200 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | 2018 School Leavers | Disease associated genogroups | 225 | 4,104 | OG000 | ClinicalTrials.gov |
| Group 2 | 2019 School Leavers | Disease associated genogroups | 134 | 2,690 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Estimate the Difference in Carriage Prevalence of Disease Associated Genogroups of N. Meningitidis (A, B, C, W, X, Y) Between School Leavers in 2018 (Year 12 in 2017) and 2019 (Year 12 in 2018), Following a 4CMenB School Immunisation Program | ClinicalTrials.gov |
| Description | As measured by PCR in school leavers in 2018 and 2019 | ClinicalTrials.gov |
| Time frame | 2018 to 2019 | ClinicalTrials.gov |
| Population | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Study to Assess Oropharyngeal Carriage of N. Meningitidis in South Australian School Leavers | ClinicalTrials.gov |
| NCT number | NCT03419533 | ClinicalTrials.gov |
| Phases | ClinicalTrials.gov | |
| Conditions | Neisseria Meningitidis | ClinicalTrials.gov |
| Interventions | ClinicalTrials.gov | |
| Lead sponsor | University of Adelaide | ClinicalTrials.gov |
| Results first posted | 2021-11-05 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT03419533?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.