Comparison · NCT03458325-ceba405c
Furoscix Infusor Prospective Treatment vs Matched Historical Control: Heart-Failure Related Emergency Department Visits
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Furoscix Infusor Prospective Treatment vs Matched Historical Control: Heart-Failure Related Emergency Department Visits. Trial comparisons, record NCT03458325-ceba405c. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03458325-ceba405c
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0417 | 0.00739 | 0.202 | wilson | |
| Risk in group 2 | 0.0606 | 0.0238 | 0.146 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0189 | -0.111 | 0.146 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.687 | 0.0808 | 5.85 | log | |
| Odds ratio, group 1 over group 2 | 0.674 | 0.0715 | 6.35 | log | |
| Number needed to treat, for one fewer participant with the outcome on Furoscix Infusor Prospective Treatment than on Matched Historical Control | 52.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Furoscix Infusor Prospective Treatment | Furoscix (furosemide injection, 8 mg/mL) administered subcutaneously over 5 hours via the Furoscix Infusor outside the hospital.~Furoscix Infusor: Furoscix Infusor, a drug-device combination product for subcutaneous delivery of Furoscix, buffered furosemide injection, 8 mg/mL (total dose = 80 mg dose) administered subcutaneously for 5 hours. | 1 | 24 | OG000 |
| Group 2 | Matched Historical Control | The control arm was populated with claims data for patients who presented to the emergency department for worsening HF and were admitted to the hospital for ≤ 72 hours for the treatment of HF. | 4 | 66 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Heart-Failure Related Emergency Department Visits
- Description
- The differences in the percentage of patients with HF-related emergency department visits in the Furoscix group and in the Control group in the 30 day follow-up period
- Time frame
- Day 0 - Day 30
- Population
- Evaluable Population
Source ClinicalTrials.gov
Trial
- Title
- Furoscix Real-World Evaluation for Decreasing Hospital Admissions in Heart Failure
- NCT number
- NCT03458325
- Phases
- PHASE3
- Conditions
- Heart Failure
- Interventions
- Furoscix Infusor
- Lead sponsor
- scPharmaceuticals, Inc.
- Results first posted
- 2023-02-24
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03458325?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT03458325-ceba405c