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Comparison · NCT03505788-e231b6dd

Acetazolamide vs Placebo: Hospital Readmission

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Acetazolamide vs Placebo: Hospital Readmission. Trial comparisons, record NCT03505788-e231b6dd. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03505788-e231b6dd

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.1840.1410.236wilson
Risk in group 20.1740.1320.225wilson
Risk difference, group 1 minus group 20.00985-0.05650.0762newcombe hybrid score
Risk ratio, group 1 over group 21.060.731.53log
Odds ratio, group 1 over group 21.070.6811.68log
Number needed to treat, for one more participant with the outcome on Acetazolamide than on Placebo102from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1AcetazolamideIn the experimental group, the patient will receive the standard of care loop diuretics and acetazolamide47256OG001
Group 2PlaceboIn the placebo group, the patient will receive the standard of care loop diuretics and the placebo45259OG000

Outcome

Type
SECONDARY
Title
Hospital Readmission
Description
If a patient is readmitted to the hospital within 3 months, this data will be collected
Time frame
3 months
Population

Source ClinicalTrials.gov

Trial

Title
Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)
NCT number
NCT03505788
Phases
PHASE4
Conditions
Acute Decompensated Heart Failure, Volume Overload
Interventions
Acetazolamide, Placebo
Lead sponsor
Ziekenhuis Oost-Limburg
Results first posted
2024-10-28

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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