Comparison · NCT03554291-deaths
Famotidine vs Placebo: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Famotidine vs Placebo: deaths from any cause. Trial comparisons, record NCT03554291-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03554291-deaths
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.05 | 0.0138 | 0.165 | wilson | |
| Risk in group 2 | 0.0256 | 0.00454 | 0.132 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0244 | -0.0878 | 0.141 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.95 | 0.184 | 20.6 | log | |
| Odds ratio, group 1 over group 2 | 2 | 0.174 | 23 | log | |
| Number needed to harm, for one more death from any cause on Famotidine than on Placebo | 41.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Famotidine | 20mg of oral famotidine (pill) daily~Other names: Pepcid~Famotidine 20 MG: Famotidine 20 mg capsule taken daily for 24 weeks. | 2 | 40 | EG000 |
| Group 2 | Placebo | Daily oral placebo (pill)~Placebo: Placebo capsule taken daily for 24 weeks. | 1 | 39 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Adverse events were collected over 24 weeks.
Source ClinicalTrials.gov
Trial
- Title
- Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension
- NCT number
- NCT03554291
- Phases
- PHASE2
- Conditions
- Pulmonary Arterial Hypertension, Right Heart Failure
- Interventions
- Famotidine 20 MG, Placebo
- Lead sponsor
- University of Washington
- Results first posted
- 2024-08-09
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03554291?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT03554291-deaths