Comparison · NCT03587142-sae
Buspirone vs Placebo: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Buspirone vs Placebo: serious adverse events. Trial comparisons, record NCT03587142-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03587142-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0213 | 0.00377 | 0.111 | wilson | |
| Risk in group 2 | 0.0204 | 0.00361 | 0.107 | wilson | |
| Risk difference, group 1 minus group 2 | 0.000868 | -0.0874 | 0.0923 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.04 | 0.0671 | 16.2 | log | |
| Odds ratio, group 1 over group 2 | 1.04 | 0.0634 | 17.2 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Buspirone than on Placebo | 1,150 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Buspirone | Buspirone HCl 10 mg capsule orally three times daily, 30 minutes before each meal, for 4-weeks~Buspirone: Buspirone tablet | 1 | 47 | EG000 |
| Group 2 | Placebo | Placebo capsule orally three times daily, 30 minutes before each meal, for 4-weeks; manufactured to look identical to buspirone capsule~Placebo: Sugar pill manufactured to mimic buspirone 10 mg tablet | 1 | 49 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Adverse events were counted after randomization through end of treatment at 4-weeks.
Source ClinicalTrials.gov
Trial
- Title
- Buspirone for Early Satiety and Symptoms of Gastroparesis
- NCT number
- NCT03587142
- Phases
- PHASE2
- Conditions
- Gastroparesis
- Interventions
- Buspirone, Placebo
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Results first posted
- 2023-06-15
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03587142?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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