Comparison · NCT03673306-4934f2be
Pregnant Cohort vs Non-pregnant Cohort: Overall Survival
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Pregnant Cohort vs Non-pregnant Cohort: Overall Survival. Trial comparisons, record NCT03673306-4934f2be. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03673306-4934f2be
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0592 | 0.0436 | 0.0799 | wilson | |
| Risk in group 2 | 0.14 | 0.13 | 0.151 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0808 | -0.0998 | -0.0576 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.423 | 0.309 | 0.579 | log | |
| Odds ratio, group 1 over group 2 | 0.387 | 0.276 | 0.541 | log | |
| Number needed to treat, for one fewer participant with the outcome on Pregnant Cohort than on Non-pregnant Cohort | 12.4 | 10 | 17.3 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Pregnant Cohort | Women with one or more pregnancies any time after breast cancer diagnosis~Clinical outcomes: Clinical outcomes | 39 | 659 | OG000 |
| Group 2 | Non-pregnant Cohort | Women with no subsequent pregnancies after breast cancer diagnosis~Clinical outcomes: Clinical outcomes | 570 | 4,073 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Overall Survival
- Description
- An overall survival event was defined as death due to any cause.
- Time frame
- 10 years
- Population
Source ClinicalTrials.gov
Trial
- Title
- Safety of Pregnancy in BRCA Mutated Breast Cancer Patients
- NCT number
- NCT03673306
- Phases
- Conditions
- Breast Cancer
- Interventions
- Clinical outcomes
- Lead sponsor
- Jules Bordet Institute
- Results first posted
- 2024-12-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03673306?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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