Comparison · NCT03673501-deaths
Ripretinib vs Sunitinib: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Ripretinib vs Sunitinib: deaths from any cause. Trial comparisons, record NCT03673501-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03673501-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.404 | 0.341 | 0.469 | wilson | |
| Risk in group 2 | 0.43 | 0.366 | 0.496 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0263 | -0.117 | 0.065 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.939 | 0.753 | 1.17 | log | |
| Odds ratio, group 1 over group 2 | 0.898 | 0.615 | 1.31 | log | |
| Number needed to treat, for one fewer death from any cause on Ripretinib than on Sunitinib | 38.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ripretinib | Ripretinib (150 mg) once a day continuous dosing for 6-week (42 days) cycles | 90 | 223 | EG000 |
| Group 2 | Sunitinib | Sunitinib (50 mg) once a day in 6-week (42 days) cycles with 4 weeks continuous dosing followed by 2 week break. | 95 | 221 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Collection of Adverse events started from the signing of informed consent through safety follow-up (up to 3.22 years)
Source ClinicalTrials.gov
Trial
- Title
- A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib
- NCT number
- NCT03673501
- Phases
- PHASE3
- Conditions
- Gastrointestinal Stromal Tumors
- Interventions
- Ripretinib, Sunitinib
- Lead sponsor
- Deciphera Pharmaceuticals, LLC
- Results first posted
- 2024-01-02
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03673501?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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