Comparison · NCT03687372-2ca110d4
Hydrogen Peroxide 45% A-101 vs Isopropyl Alcohol and Water Vehicle: Number of Subjects With a Single Wart at Baseline Whose Wart Was Clear on the PWA Scale Between Active and Vehicle Group (PWA=0) at Visit 10 (Day 60)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Hydrogen Peroxide 45% A-101 vs Isopropyl Alcohol and Water Vehicle: Number of Subjects With a Single Wart at Baseline Whose Wart Was Clear on the PWA Scale Between Active and Vehicle Group (PWA=0) at Visit 10 (Day 60). Trial comparisons, record NCT03687372-2ca110d4. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03687372-2ca110d4
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.204 | 0.149 | 0.272 | wilson | |
| Risk in group 2 | 0.0709 | 0.039 | 0.126 | wilson | |
| Risk difference, group 1 minus group 2 | 0.133 | 0.0553 | 0.208 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 2.87 | 1.47 | 5.62 | log | |
| Odds ratio, group 1 over group 2 | 3.35 | 1.59 | 7.08 | log | |
| Number needed to treat, for one more participant with the outcome on Hydrogen Peroxide 45% A-101 than on Isopropyl Alcohol and Water Vehicle | 7.53 | 4.8 | 18.1 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Hydrogen Peroxide 45% A-101 | Topical solution, hydrogen peroxide 45% A-101: hydrogen peroxide 45% topical solution | 33 | 162 | OG000 |
| Group 2 | Isopropyl Alcohol and Water Vehicle | Topical solution, isopropyl alcohol and water Vehicle: Vehicle solution containing isopropyl alcohol and water | 10 | 141 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Subjects With a Single Wart at Baseline Whose Wart Was Clear on the PWA Scale Between Active and Vehicle Group (PWA=0) at Visit 10 (Day 60)
- Description
Comparison between Active (A-101 45%) and Vehicle of subjects with a single wart at baseline, whose wart is clear (PWA=0) at Day 60.~Clearance of the single wart at baseline will be assessed using the Physician Wart Assessment (PWA) scale which is a four point scale. A higher amount of warts cleared represents a better outcome.
- Time frame
- Day 60
- Population
Source ClinicalTrials.gov
Trial
- Title
- Study of A-101 Topical Solution for the Treatment of Common Warts
- NCT number
- NCT03687372
- Phases
- PHASE3
- Conditions
- Common Wart
- Interventions
- A-101, vehicle
- Lead sponsor
- Aclaris Therapeutics, Inc.
- Results first posted
- 2020-10-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03687372?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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