Comparison · NCT03691831-2ca110d4
Active vs Vehicle: Number of Subjects With a Single Wart at Baseline Whose Wart Was Clear on the PWA Scale Between Active and Vehicle Group (PWA=0) at Visit 10 (Day 60)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Active vs Vehicle: Number of Subjects With a Single Wart at Baseline Whose Wart Was Clear on the PWA Scale Between Active and Vehicle Group (PWA=0) at Visit 10 (Day 60). Trial comparisons, record NCT03691831-2ca110d4. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03691831-2ca110d4
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.151 | 0.0987 | 0.224 | wilson | |
| Risk in group 2 | 0.0282 | 0.011 | 0.0702 | wilson | |
| Risk difference, group 1 minus group 2 | 0.123 | 0.0557 | 0.197 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 5.35 | 1.87 | 15.3 | log | |
| Odds ratio, group 1 over group 2 | 6.13 | 2.02 | 18.5 | log | |
| Number needed to treat, for one more participant with the outcome on Active than on Vehicle | 8.15 | 5.07 | 18 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: vehicle.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Active | Topical solution, hydrogen peroxide 45%~A-101: hydrogen peroxide 45% topical solution | 19 | 126 | OG000 |
| Group 2 | Vehicle | Topical solution, isopropyl alcohol and water~Vehicle: Vehicle solution containing isopropyl alcohol and water | 4 | 142 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Subjects With a Single Wart at Baseline Whose Wart Was Clear on the PWA Scale Between Active and Vehicle Group (PWA=0) at Visit 10 (Day 60)
- Description
Comparison between Active (A-101 45%) and Vehicle of subjects with a single wart at baseline, whose wart is clear (PWA=0) at Day 60.~Clearance of the single wart at baseline will be assessed using the Physician Wart Assessment (PWA) scale which is a four point scale. A higher amount of warts cleared represents a better outcome.
- Time frame
- Day 60
- Population
Source ClinicalTrials.gov
Trial
- Title
- A Study of A-101 Topical Solution for the Treatment of Common Warts
- NCT number
- NCT03691831
- Phases
- PHASE3
- Conditions
- Common Wart
- Interventions
- Active, Vehicle
- Lead sponsor
- Aclaris Therapeutics, Inc.
- Results first posted
- 2020-10-05
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03691831?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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