Comparison · NCT03694002-deaths
Experimental: Arm A (Ramucirumab, Carboplatin, Paclitaxel) vs Active Comparator: Arm B (Carboplatin, Paclitaxel): deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Experimental: Arm A (Ramucirumab, Carboplatin, Paclitaxel) vs Active Comparator: Arm B (Carboplatin, Paclitaxel): deaths from any cause. Trial comparisons, record NCT03694002-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03694002-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.125 | 0.0224 | 0.471 | wilson | |
| Risk in group 2 | 0.222 | 0.0632 | 0.547 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0972 | -0.438 | 0.283 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.563 | 0.0621 | 5.09 | log | |
| Odds ratio, group 1 over group 2 | 0.5 | 0.0364 | 6.86 | log | |
| Number needed to treat, for one fewer death from any cause on Experimental: Arm A (Ramucirumab, Carboplatin, Paclitaxel) than on Active Comparator: Arm B (Carboplatin, Paclitaxel) | 10.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Experimental: Arm A (Ramucirumab, Carboplatin, Paclitaxel) | Patients receive ramucirumab IV over 60 minutes, carboplatin IV, and paclitaxel IV on day 1. Treatment repeats every 21 days for up to 6 cycles in the absence of disease progression or unacceptable toxicity. Patients who have not progressed may continue to receive ramucirumab for up to 1 year. | 1 | 8 | EG000 |
| Group 2 | Active Comparator: Arm B (Carboplatin, Paclitaxel) | Patients receive carboplatin IV and paclitaxel IV on day 1. Treatment repeats every 21 days for up to 6 cycles in the absence of disease progression or unacceptable toxicity. | 2 | 9 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Up to 2 years after randomization
Source ClinicalTrials.gov
Trial
- Title
- Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery
- NCT number
- NCT03694002
- Phases
- PHASE2
- Conditions
- Locally Advanced Thymic Carcinoma, Metastatic Thymic Carcinoma, Recurrent Thymic Carcinoma, Unresectable Thymic Carcinoma
- Interventions
- Carboplatin, Paclitaxel, Ramucirumab
- Lead sponsor
- SWOG Cancer Research Network
- Results first posted
- 2025-10-30
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03694002?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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GET https://conductscience.org/api/comparisons/v1/NCT03694002-deaths