Comparison · NCT03745898-sae
Nocturnal Oxygen Therapy vs Sham Nocturnal Oxygen Therapy: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Nocturnal Oxygen Therapy vs Sham Nocturnal Oxygen Therapy: serious adverse events. Trial comparisons, record NCT03745898-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03745898-sae
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.542 | 0.403 | 0.674 | wilson | |
| Risk in group 2 | 0.44 | 0.312 | 0.577 | wilson | |
| Risk difference, group 1 minus group 2 | 0.102 | -0.0933 | 0.286 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.23 | 0.82 | 1.85 | log | |
| Odds ratio, group 1 over group 2 | 1.5 | 0.678 | 3.34 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Nocturnal Oxygen Therapy than on Sham Nocturnal Oxygen Therapy | 9.84 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: sham.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Nocturnal Oxygen Therapy | Active nocturnal oxygen therapy~Oxygen: Active nocturnal oxygen concentrator | 26 | 48 | EG000 |
| Group 2 | Sham Nocturnal Oxygen Therapy | Sham nocturnal oxygen therapy (room air)~Room Air: Sham nocturnal oxygen concentrator (room air) | 22 | 50 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Participants were monitored for adverse events from study enrollment through all follow-up study visits (baseline, 3 month, 6 month, 9 month 12 month, 18 month, 24 month) until study termination.
Source ClinicalTrials.gov
Trial
- Title
- The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
- NCT number
- NCT03745898
- Phases
- PHASE3
- Conditions
- Heart Failure, Central Sleep Apnea
- Interventions
- Oxygen, Room Air
- Lead sponsor
- Brigham and Women's Hospital
- Results first posted
- 2023-08-01
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03745898?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT03745898-sae