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Comparison · NCT03808818-66a483a7

EUC (Smoking Assessment, Quitting Advice, Quitline Referral) vs VST (Virtual Counseling Sessions, NRT): Significant Reduction in Smoking

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. EUC (Smoking Assessment, Quitting Advice, Quitline Referral) vs VST (Virtual Counseling Sessions, NRT): Significant Reduction in Smoking. Trial comparisons, record NCT03808818-66a483a7. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03808818-66a483a7

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.3290.2570.409wilson
Risk in group 20.4320.3550.513wilson
Risk difference, group 1 minus group 2-0.104-0.2120.00778newcombe hybrid score
Risk ratio, group 1 over group 20.760.5641.02log
Odds ratio, group 1 over group 20.6430.3991.04log
Number needed to treat, for one fewer participant with the outcome on EUC (Smoking Assessment, Quitting Advice, Quitline Referral) than on VST (Virtual Counseling Sessions, NRT)9.64from the risk difference intervalthe interval includes no difference

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1EUC (Smoking Assessment, Quitting Advice, Quitline Referral)
Enhanced usual care (EUC) participants receive an assessment of smoking status and provision of quitting advice through the screening and referral process, and are referred to the NCI Smoking Quitline.~Behavioral, Psychological or Informational Intervention: Receive information about tobacco cessation Quality-of-Life Assessment: Ancillary studies
47143OG000
Group 2VST (Virtual Counseling Sessions, NRT)
Virtual Sustained Treatment (VST) patients receive an initial virtual counseling session with a study-designated tobacco treatment coach via MGH TeleHealth over 40 minutes and up to 10 more virtual counseling sessions over 15 minutes for approximately 6 months. Patients also receive up to 12 weeks of NRT (patch and lozenge combined or alone).~Nicotine Replacement: Given NRT patch or lozenge (or both) Quality-of-Life Assessment: Ancillary studies Survey Administration: Ancillary studies Tobacco Cessation Counseling: Receive virtual tobacco cessation counseling
64148OG001

Outcome

Type
SECONDARY
Title
Significant Reduction in Smoking
Description
Significant reduction in daily smoking from baseline to 6 months was defined as \> 50% reduction in reported number of cigarettes per day.~Patients were ask to report the average number of cigarettes smoked per day on the 6mo and baseline surveys.~if Xb is the average number smoked at baseline and X6 is the average number smoked at 6 months Then the reduction was calculated as (Xb-X6)/Xb
Time frame
baseline and 6 months
Population

Source ClinicalTrials.gov

Trial

Title
Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices
NCT number
NCT03808818
Phases
NA
Conditions
Carcinoma In Situ, Current Smoker, Malignant Neoplasm, Primary Neoplasm, Recurrent Neoplasm, Smoking Cessation
Interventions
Behavioral, Psychological or Informational Intervention, Nicotine Replacement, Quality-of-Life Assessment, Survey Administration, Tobacco Cessation Counseling
Lead sponsor
ECOG-ACRIN Cancer Research Group
Results first posted
2025-03-18

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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