Comparison · NCT03831880-e1d2840e
Genotropin vs Somatrogon: Number of Participants With Discontinuation Due to Adverse Events (AEs)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Genotropin vs Somatrogon: Number of Participants With Discontinuation Due to Adverse Events (AEs). Trial comparisons, record NCT03831880-e1d2840e. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT03831880-e1d2840e
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0 | 0 | 0.0428 | wilson | |
| Risk in group 2 | 0.0115 | 0.00203 | 0.0623 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0115 | -0.0623 | 0.0323 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one fewer participant with the outcome on Genotropin than on Somatrogon | 87 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Genotropin | Participants received Genotropin, daily subcutaneously, in overall study (either in Period 1 or in Period 2). | 0 | 86 | OG000 |
| Group 2 | Somatrogon | Participants received Somatrogon, weekly subcutaneously, at a dose of 0.66 mg/kg/week, in overall study (either in Period 1 or in Period 2). | 1 | 87 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- OTHER_PRE_SPECIFIED
- Title
- Number of Participants With Discontinuation Due to Adverse Events (AEs)
- Description
An AE was any untoward medical occurrence in a participant who received study drug without regard to possibility of causal relationship. The discontinuations due to adverse events was defined for participants and reported in this outcome measure.
- Time frame
- Baseline up to 35 days after last dose of study drug (up to 29 Weeks)
- Population
- The safety analysis set included all participants who received at least 1 dose of study intervention. The participants were analyzed according to the intervention they actually received.
Source ClinicalTrials.gov
Trial
- Title
- Patient Perception of Treatment Burden in Weekly Versus Daily Growth Hormone Injections in Children With GHD
- NCT number
- NCT03831880
- Phases
- PHASE3
- Conditions
- Growth Hormone Deficiency
- Interventions
- Genotropin, somatrogon
- Lead sponsor
- Pfizer
- Results first posted
- 2021-10-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT03831880?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT03831880-e1d2840e