Pharmacist Arm vs Usual Care: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.458 | 0.441 | 0.476 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.444 | 0.427 | 0.461 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.0145 | -0.00972 | 0.0387 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.03 | 0.979 | 1.09 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.06 | 0.961 | 1.17 | log | ClinicalTrials.gov | |
| Number needed to harm, for one more participant with a serious adverse event on Pharmacist Arm than on Usual Care | 68.9 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Pharmacist Arm | Pharmacist-Led Medication Reconciliation, Regimen Review, and Adherence and Literacy Assessment and Counseling~Pharmacist-led Hospital Discharge Care Intervention: Pharmacists will address medication reconciliation, medication adherence, and polypharmacy issues as appropriate. Pharmacists will rely most on their prior training, but study investigators will also encourage the use of documentation templates with reminders, Beers list, deprescribing, motivational interviewing, the Medication Adherence and Literacy tool, and post-discharge phone calls.~Pharmacists will assess patient needs and customize accordingly. All patients will receive one discharge counseling visit and one post-discharge phone call, but pharmacists will find that some patients need further phone calls, interventions, referrals, or other interactions. Some or all of the pharmacist activities may take place over the phone. | 1,485 | 3,239 | EG000 | ClinicalTrials.gov |
| Group 2 | Usual Care | Patients in this study will receive usual care. Clinically-indicated services, including pharmacist services, may be provided to control group patients. | 1,438 | 3,239 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, serious adverse events | ClinicalTrials.gov |
| Time frame | From the time of randomization (near hospital admission) up to 90 days after hospital discharge | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Pharmacist Intervention to Reduce Post-Hospitalization Utilization | ClinicalTrials.gov |
| NCT number | NCT04071951 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Nonadherence, Patient, Polypharmacy, Readmission | ClinicalTrials.gov |
| Interventions | Pharmacist-led Hospital Discharge Care Intervention | ClinicalTrials.gov |
| Lead sponsor | Cedars-Sinai Medical Center | ClinicalTrials.gov |
| Results first posted | 2024-10-29 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT04071951?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.