Immediate Return of Results (Intent to Treat, ITT) vs Delayed Return of Results (Intent to Treat, ITT): deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.00385 | 0.00225 | 0.00657 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.00356 | 0.00204 | 0.00621 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.00029 | -0.0028 | 0.00341 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.08 | 0.494 | 2.37 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.08 | 0.493 | 2.37 | log | ClinicalTrials.gov | |
| Number needed to harm, for one more death from any cause on Immediate Return of Results (Intent to Treat, ITT) than on Delayed Return of Results (Intent to Treat, ITT) | 3,450 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Immediate Return of Results (Intent to Treat, ITT) | Immediate return of results to inform participant of APOL1 status (either positive or negative). | 13 | 3,380 | EG000 | ClinicalTrials.gov |
| Group 2 | Delayed Return of Results (Intent to Treat, ITT) | Delayed return of results of APOL1 status (either positive or negative) after the completion of the 6 month final study visit. | 12 | 3,374 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, all-cause mortality | ClinicalTrials.gov |
| Time frame | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Genetic Testing to Understand and Address Renal Disease Disparities Across the United States | ClinicalTrials.gov |
| NCT number | NCT04191824 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Chronic Kidney Disease, Hypertension | ClinicalTrials.gov |
| Interventions | Timing of return of results | ClinicalTrials.gov |
| Lead sponsor | Duke University | ClinicalTrials.gov |
| Results first posted | 2025-04-30 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT04191824?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.