Receives OUD-CDS vs Does Not Receive the OUD-CDS: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.658 | 0.645 | 0.67 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.681 | 0.669 | 0.693 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0235 | -0.0409 | -0.00611 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.965 | 0.941 | 0.991 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.899 | 0.831 | 0.973 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with a serious adverse event on Receives OUD-CDS than on Does Not Receive the OUD-CDS | 42.5 | 24.4 | 164 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Receives OUD-CDS | Clinics will have access to the OUD-CDS (Opioid Wizard)~Opioid Wizard: The Opioid Wizard is an OUD clinical decision support tool for primary care providers to help assess, diagnose, and treat OUD in primary care (where appropriate). | 3,740 | 5,688 | EG000 | ClinicalTrials.gov |
| Group 2 | Does Not Receive the OUD-CDS | Clinics will not have access to the OUD-CDS (Opioid Wizard). These will be usual care clinics. | 3,752 | 5,509 | EG001 | ClinicalTrials.gov |
Harm 2
| Field | Value | Source |
|---|---|---|
| What it counts | Total, serious adverse events | ClinicalTrials.gov |
| Time frame | pre: one year through one day prior to the index visit; post: index visit through December 31, 2023 or date of death, whichever was first, up to 33 months | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0) | ClinicalTrials.gov |
| NCT number | NCT04198428 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Opioid-use Disorder | ClinicalTrials.gov |
| Interventions | Opioid Wizard | ClinicalTrials.gov |
| Lead sponsor | HealthPartners Institute | ClinicalTrials.gov |
| Results first posted | 2025-10-02 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT04198428?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.