E-MOTIVE Intervention vs Usual Care: Postpartum Laparotomy for Bleeding Until Discharge From the Health Facility
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.000244 | 0.00014 | 0.000427 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.000138 | 0.0000671 | 0.000286 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.000106 | -0.0000747 | 0.000302 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.77 | 0.695 | 4.48 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.77 | 0.695 | 4.48 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on E-MOTIVE Intervention than on Usual Care | 9,440 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | E-MOTIVE Intervention | The E-MOTIVE intervention consists of three elements: 1) a strategy for early detection of PPH, which allows triggering of the 'first response' treatment bundle; 2) a 'first response' bundle called MOTIVE, based on the WHO guideline recommendations and consisting of uterine Massage, Oxytocic drugs, Tranexamic acid, IV fluids and Examination \& Escalation; and 3) an implementation strategy, focusing on simulation-based training with peer-assisted learning, local E-MOTIVE champions, feedback of actionable data to providers, calibrated drape with trigger line, and MOTIVE emergency trolley and/or carry case. | 12 | 49,101 | OG000 | ClinicalTrials.gov |
| Group 2 | Usual Care | Usual care with dissemination of the current guidelines~Usual care: Health facilities will continue to follow usual care as per the baseline period for the remainder of the intervention phase. | 7 | 50,558 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | SECONDARY | ClinicalTrials.gov |
| Title | Postpartum Laparotomy for Bleeding Until Discharge From the Health Facility | ClinicalTrials.gov |
| Description | ClinicalTrials.gov | |
| Time frame | Postpartum until discharge from the health facility (up to 42 days). | ClinicalTrials.gov |
| Population | Number of women | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth | ClinicalTrials.gov |
| NCT number | NCT04341662 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Post-Partum Haemorrhage | ClinicalTrials.gov |
| Interventions | E-MOTIVE intervention, Usual care | ClinicalTrials.gov |
| Lead sponsor | University of Birmingham | ClinicalTrials.gov |
| Results first posted | 2024-08-06 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT04341662?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.