Comparison · NCT04343521-sae
Targeted Indoor Residual Spraying (TIRS) vs Routine Aedes-borne Virus (ABV) Prevention and Control: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Targeted Indoor Residual Spraying (TIRS) vs Routine Aedes-borne Virus (ABV) Prevention and Control: serious adverse events. Trial comparisons, record NCT04343521-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04343521-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0 | 0 | 0.00171 | wilson | |
| Risk in group 2 | 0.0009 | 0.000247 | 0.00328 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0009 | -0.00328 | 0.000933 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | log | a group has no participants with the outcome | |||
| Odds ratio, group 1 over group 2 | log | a cell of the two-by-two table is zero | |||
| Number needed to treat, for one fewer participant with a serious adverse event on Targeted Indoor Residual Spraying (TIRS) than on Routine Aedes-borne Virus (ABV) Prevention and Control | 1,111 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Targeted Indoor Residual Spraying (TIRS) | Children residing in households located in Targeted Indoor Residual Spraying (TIRS) clusters that were offered the intervention. | 0 | 2,239 | EG000 |
| Group 2 | Routine Aedes-borne Virus (ABV) Prevention and Control | Children residing in households located in routine Aedes-borne virus (ABV) prevention and control clusters, without Targeted Indoor Residual Spraying (TIRS). | 2 | 2,222 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Information on adverse events was collected beginning at the time when individuals gave consent to participate in the study and continued through the final assessment (up to 41 months and 26 days).
Source ClinicalTrials.gov
Trial
- Title
- Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne Diseases
- NCT number
- NCT04343521
- Phases
- NA
- Conditions
- Aedes-borne Diseases, Dengue, Chikungunya, Zika
- Interventions
- Targeted Indoor Residual Spraying (TIRS)
- Lead sponsor
- Emory University
- Results first posted
- 2025-09-18
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04343521?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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