Comparison · NCT04350593-deaths
Dapagliflozin 10mg vs Placebo: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Dapagliflozin 10mg vs Placebo: deaths from any cause. Trial comparisons, record NCT04350593-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04350593-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0656 | 0.0487 | 0.0878 | wilson | |
| Risk in group 2 | 0.0864 | 0.0668 | 0.111 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0208 | -0.0507 | 0.00879 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.759 | 0.514 | 1.12 | log | |
| Odds ratio, group 1 over group 2 | 0.742 | 0.487 | 1.13 | log | |
| Number needed to treat, for one fewer death from any cause on Dapagliflozin 10mg than on Placebo | 48.1 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Dapagliflozin 10mg | Dapagliflozin 10 mg daily~Dapagliflozin 10 MG: Active Comparator: Dapagliflozin 10mg | 41 | 625 | EG000 |
| Group 2 | Placebo | Dapagliflozin matching placebo 10 mg daily~Placebo: Placebo Comparator | 54 | 625 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- Adverse events were collected from the time of signing informed consent through the end of the 30-day treatment period.
Source ClinicalTrials.gov
Trial
- Title
- Dapagliflozin in Respiratory Failure in Patients With COVID-19
- NCT number
- NCT04350593
- Phases
- PHASE3
- Conditions
- COVID-19
- Interventions
- Dapagliflozin 10 milligram (mg), Placebo
- Lead sponsor
- Saint Luke's Health System
- Results first posted
- 2022-04-13
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04350593?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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