Comparison · NCT04392375-e097d487
Nifedipine 30MG vs Placebo: Number of Participants With the Change in Blood Pressure (Both Systolic and Diastolic) Under the Treatment of NIfedipine 30mg XL Versus Placebo
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Nifedipine 30MG vs Placebo: Number of Participants With the Change in Blood Pressure (Both Systolic and Diastolic) Under the Treatment of NIfedipine 30mg XL Versus Placebo. Trial comparisons, record NCT04392375-e097d487. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04392375-e097d487
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.34 | 0.227 | 0.474 | wilson | |
| Risk in group 2 | 0.551 | 0.413 | 0.681 | wilson | |
| Risk difference, group 1 minus group 2 | -0.211 | -0.384 | -0.0188 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.616 | 0.392 | 0.969 | log | |
| Odds ratio, group 1 over group 2 | 0.419 | 0.188 | 0.933 | log | |
| Number needed to treat, for one fewer participant with the outcome on Nifedipine 30MG than on Placebo | 4.73 | 2.61 | 53.1 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Nifedipine 30MG | Oral administration of 30mg Nifedipine XL q24 hours until delivery~Nifedipine 30 MG: Nifedipine XL is a long-acting medication used to lower blood pressure. The investigators want to learn whether women who receive the study drug will experience fewer severe-range blood pressure readings, and therefore need fewer intravenous (IV) medications to safely lower blood pressure. | 18 | 53 | OG000 |
| Group 2 | Placebo | Matching placebo group q24hrs until delivery~Placebos: At the time of enrollment, patients will be randomized to either the study drug (oral Nifedipine XL 30mg) or identical placebo. | 27 | 49 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants With the Change in Blood Pressure (Both Systolic and Diastolic) Under the Treatment of NIfedipine 30mg XL Versus Placebo
- Description
- Measured acute antihypertension therapy between enrollment and delivery
- Time frame
- Between enrollment and delivery, assessed up to 18 weeks
- Population
Source ClinicalTrials.gov
Trial
- Title
- Nifedipine XL Versus Placebo for the Treatment of Preeclampsia With Severe Features During Induction of Labor
- NCT number
- NCT04392375
- Phases
- PHASE4
- Conditions
- Preeclampsia Severe
- Interventions
- Nifedipine 30 MG, Placebos
- Lead sponsor
- Ohio State University
- Results first posted
- 2023-07-24
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04392375?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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