Comparison · NCT04406714-a9b88c91
Trial Mailed FIT Intervention - Age Group 45-49 vs Trial Usual Care - Age Group 45-49: Proportion of Subjects, Ages 45-49, Who Completed Mailed FIT at 60 Days
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Trial Mailed FIT Intervention - Age Group 45-49 vs Trial Usual Care - Age Group 45-49: Proportion of Subjects, Ages 45-49, Who Completed Mailed FIT at 60 Days. Trial comparisons, record NCT04406714-a9b88c91. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04406714-a9b88c91
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.215 | 0.158 | 0.286 | wilson | |
| Risk in group 2 | 0.127 | 0.0835 | 0.187 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0886 | 0.00529 | 0.171 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.7 | 1.02 | 2.82 | log | |
| Odds ratio, group 1 over group 2 | 1.89 | 1.03 | 3.46 | log | |
| Number needed to treat, for one more participant with the outcome on Trial Mailed FIT Intervention - Age Group 45-49 than on Trial Usual Care - Age Group 45-49 | 11.3 | 5.84 | 189 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: usual care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Trial Mailed FIT Intervention - Age Group 45-49 | Subjects randomized to this arm are 45-49 years of age and eligible for CRC screening using FIT per electronic health record at one site.~Trial Mailed FIT Intervention - Age Group 45- 49: Subjects are mailed an introductory letter advising them that they will receive an FIT kit in the mail. Next, subjects are mailed a FIT packet in an envelope that contains a cover letter, CRC information sheet, FIT instruction sheet, and FIT kit with a pre-paid return envelope. Subjects receive up to two mailed letters reminding them to complete and return the FIT. Subjects receive FIT results via letter or phone call. | 34 | 158 | OG000 |
| Group 2 | Trial Usual Care - Age Group 45-49 | Subjects randomized to this arm are 45-49 years of age and eligible for CRC screening using FIT per electronic health record at one site. | 20 | 158 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Proportion of Subjects, Ages 45-49, Who Completed Mailed FIT at 60 Days
- Description
The proportion of subjects in Arm 3 (Intervention Enhanced Envelope - Age Group 45-49) compared to subjects in Arm 4 (Intervention Active Comparator Envelope - Age Group 45-49) who returned a completed FIT.
- Time frame
- 60 days after randomization
- Population
- Subjects who are between 45-49 old completed mailed FIT at 60 days
Source ClinicalTrials.gov
Trial
- Title
- Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
- NCT number
- NCT04406714
- Phases
- NA
- Conditions
- Colorectal Cancer
- Interventions
- Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Results first posted
- 2024-06-25
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04406714?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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