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Comparison · NCT04410328-3c9e8af0

Participants Receiving Dipyridamole and Aspirin vs Participants Receiving Standard of Care: ICU Stay

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Participants Receiving Dipyridamole and Aspirin vs Participants Receiving Standard of Care: ICU Stay. Trial comparisons, record NCT04410328-3c9e8af0. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04410328-3c9e8af0

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.1020.04440.218wilson
Risk in group 20.1430.0710.267wilson
Risk difference, group 1 minus group 2-0.0408-0.1770.0953newcombe hybrid score
Risk ratio, group 1 over group 20.7140.2432.1log
Odds ratio, group 1 over group 20.6820.2012.32log
Number needed to treat, for one fewer participant with the outcome on Participants Receiving Dipyridamole and Aspirin than on Participants Receiving Standard of Care24.5from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: standard of care.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Participants Receiving Dipyridamole and Aspirin
Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally plus standard care. Participants will receive Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally), 2 times daily starting on the day of enrollment for a total of 2 weeks.~Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally AND Standard of care: Participants in the experimental group will receive Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally (if they have a feeding tube), 2 times daily starting on the day of enrollment for a total of 2 weeks.~Standard of care: Participants will receive standard care starting on the day of enrollment for a total of 2 weeks.
549OG000
Group 2Participants Receiving Standard of Care
Participants will receive standard care starting on the day of enrollment for a total of 2 weeks.~Standard of care: Participants will receive standard care starting on the day of enrollment for a total of 2 weeks.
749OG001

Outcome

Type
SECONDARY
Title
ICU Stay
Description
Number of participants admitted to ICU
Time frame
28 days
Population

Source ClinicalTrials.gov

Trial

Title
Aggrenox To Treat Acute Covid-19
NCT number
NCT04410328
Phases
PHASE3
Conditions
Covid19
Interventions
Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally AND Standard of care, Standard of care
Lead sponsor
Rutgers, The State University of New Jersey
Results first posted
2025-02-21

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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