Comparison · NCT04410328-f8c207e6
Participants Receiving Dipyridamole and Aspirin vs Participants Receiving Standard of Care: Number of Participants Not Requiring Supplemental Oxygen
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Participants Receiving Dipyridamole and Aspirin vs Participants Receiving Standard of Care: Number of Participants Not Requiring Supplemental Oxygen. Trial comparisons, record NCT04410328-f8c207e6. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT04410328-f8c207e6
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.918 | 0.808 | 0.968 | wilson | |
| Risk in group 2 | 0.878 | 0.758 | 0.943 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0408 | -0.0872 | 0.171 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.05 | 0.915 | 1.2 | log | |
| Odds ratio, group 1 over group 2 | 1.57 | 0.414 | 5.95 | log | |
| Number needed to treat, for one more participant with the outcome on Participants Receiving Dipyridamole and Aspirin than on Participants Receiving Standard of Care | 24.5 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: standard of care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Participants Receiving Dipyridamole and Aspirin | Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally plus standard care. Participants will receive Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally), 2 times daily starting on the day of enrollment for a total of 2 weeks.~Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally AND Standard of care: Participants in the experimental group will receive Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally (if they have a feeding tube), 2 times daily starting on the day of enrollment for a total of 2 weeks.~Standard of care: Participants will receive standard care starting on the day of enrollment for a total of 2 weeks. | 45 | 49 | OG000 |
| Group 2 | Participants Receiving Standard of Care | Participants will receive standard care starting on the day of enrollment for a total of 2 weeks.~Standard of care: Participants will receive standard care starting on the day of enrollment for a total of 2 weeks. | 43 | 49 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants Not Requiring Supplemental Oxygen
- Description
- number of participants who received supplemental oxygen or those with supplemental oxygen-free days
- Time frame
- 28 days
- Population
Source ClinicalTrials.gov
Trial
- Title
- Aggrenox To Treat Acute Covid-19
- NCT number
- NCT04410328
- Phases
- PHASE3
- Conditions
- Covid19
- Interventions
- Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally AND Standard of care, Standard of care
- Lead sponsor
- Rutgers, The State University of New Jersey
- Results first posted
- 2025-02-21
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT04410328?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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