VAX-MOM Intervention vs Standard of Care: Rate of Tdap Vaccination
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.756 | 0.745 | 0.767 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.806 | 0.796 | 0.815 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.0492 | -0.0636 | -0.0348 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.939 | 0.922 | 0.956 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.749 | 0.689 | 0.815 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with the outcome on VAX-MOM Intervention than on Standard of Care | 20.3 | 15.7 | 28.7 | from the risk difference interval | ClinicalTrials.gov |
Groups 2
Group 2 names the comparator: standard of care.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | VAX-MOM Intervention | VAX-MOM Intervention: The multi-component VAX-MOM intervention will be comprised of: training in communication, provider prompts, standing orders, and feedback on vaccination rates. | 4,532 | 5,992 | OG000 | ClinicalTrials.gov |
| Group 2 | Standard of Care | Standard of Care: Standard vaccine education and processes provided to patients by obstetric practices. | 5,452 | 6,768 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Rate of Tdap Vaccination | ClinicalTrials.gov |
| Description | Tdap vaccination rate during pregnancy. Vaccination status will be obtained from patient electronic health records. | ClinicalTrials.gov |
| Time frame | 7/1/2021 - 6/30/2022 (intervention period) | ClinicalTrials.gov |
| Population | Pregnant individuals during study period | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Increasing Influenza and Tdap Vaccination of Pregnant Women | ClinicalTrials.gov |
| NCT number | NCT04444518 | ClinicalTrials.gov |
| Phases | NA | ClinicalTrials.gov |
| Conditions | Immunization; Infection, Pregnancy Related | ClinicalTrials.gov |
| Interventions | VAX-MOM Intervention, Standard of Care | ClinicalTrials.gov |
| Lead sponsor | University of Rochester | ClinicalTrials.gov |
| Results first posted | 2025-01-10 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT04444518?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.